The Latest Advance in Probiotic Technology
Our modern world exposes us to many factors that upset the natural balance of our gastrointestinal tract, which can cause health problems, uncomfortable GI symptoms, and nutritional deficiencies. Most probiotic supplements are simply a collection of different probiotic strains with little thought about how those strains interact or how they are delivered to your digestive tract. Probiotic XL is scientifically designed to provide the ten most important live probiotic strains and to create an internal environment where they are able to thrive.
Probiotic XL is a unique triple action formula designed to provide you and your family with optimal digestive, immune, and over-all health.
Scientifically formulated to provide:
• 10 beneficial probiotic strains
• 10 billion colony forming units (CFU) of live probiotics, chosen for their specific benefit
• A prebiotic blend, a patent-pending ingredient which has been scientifically shown to support the growth of beneficial probiotics over harmful bacterial strains quickly and effectively.
• Employs Protective Shield Technology to help ensure probiotics survive the harsh conditions of the stomach, as well as manufacturing, shipping, and storage.
Great HealthWorks ProbioticXL Is designed to help support:
• Digestive and overall health1,2,3,4
• Protection from harmful levels of toxins5,6
• A healthy immune system7,8,9,10
• Positive mood and limit feelings of nervousness11,12,13,14
1 de Vrese M, Schrezenmeir J. Probiotics, prebiotics, and synbiotics. InFood biotechnology 2008 (pp. 1-66). Springer Berlin Heidelberg.
2 Ringel Y, Ringel-Kulka T, Maier D, et al. Probiotic bacteria: probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 versus placebo for the symptoms of bloating in patients With functional bowel disorders - a double-blind study. J Clin Gastroenterol 2011;45:518-25
3 Kajander K, Myllyluoma E, Rajilic-Stojanovic M, et al. Clinical trial: multispecies probiotic supplementation alleviates the symptoms of irritable bowel syndrome and stabilizes intestinal microbiota. Aliment Pharmacol Ther 2008;27:48-57.
4 Eloe-Fadrosh EA, Brady A, Crabtree J, Drabek EF, Ma B, Mahurkar A, Ravel J, Haverkamp M, Fiorino AM, Botelho C, Andreyeva I. Functional dynamics of the gut microbiome in elderly people during probiotic consumption. MBio. 2015 May 1;6(2):e00231-15.
5 Buffie CG, Pamer EG. Microbiota-mediated colonization resistance against intestinal pathogens. Nature Reviews Immunology. 2013 Nov 1;13(11):790-801.
6 Pothoulakis C, Kelly CP, Joshi MA, et al. Saccharomyces boulardii inhibits Clostridium difficile toxin A binding and enterotoxicity in rat ileum. Gastroenterology 1993;104:1108-15.
7 Smith TJ, Rigassio-Radler D, Denmark R, Haley T, Touger-Decker R. Effect of Lactobacillus rhamnosus LGG® and Bifidobacterium animalis ssp. lactis BB-12® on health-related quality of life in college students affected by upper respiratory infections. British Journal of Nutrition. 2013 Jun 14;109(11):1999-2007.
8 Round JL, Mazmanian SK. The gut microbiota shapes intestinal immune responses during health and disease. Nature Reviews Immunology. 2009 May 1;9(5):313-23.
9 Cazzola M, Pham-Thi N, Kerihuel JC, et al. Efficacy of a synbiotic supplementation in the prevention of common winter diseases in children: a randomized, double-blind, placebo-controlled pilot study. Ther Adv Respir Dis 2010;4:271-8.
10 Mubasher ME, et al. Probiotic effects on cold and influenza-like symptom incidence and duration in children. Pediatrics 2009;124:e172-9.
11 Steenbergen L, Sellaro R, van Hemert S, Bosch JA, Colzato LS. A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood. Brain, behavior, and immunity. 2015 Aug 31;48:258-64.
12 Lyte M. Probiotics function mechanistically as delivery vehicles for neuroactive compounds: microbial endocrinology in the design and use of probiotics. Bioessays. 2011 Aug 1;33(8):574-81.
13 Reid G. Neuroactive probiotics. Bioessays. 2011 Aug 1;33(8):562.
14 Dinan TG, Stanton C, Cryan JF. Psychobiotics: a novel class of psychotropic. Biological psychiatry. 2013 Nov 15;74(10):720-6.